He will be assisted by Filippo Meli and Alessio Berti in the 8pm BST kick-off.
Matteo Marcenaro will serve as the fourth official.
Marco Di Bello is on VAR duty and Daniele Chiffi is the assistant VAR.
Referee and match officials confirmed for Liverpool v Atletico Madrid
Davide Massa will referee Liverpool's Champions League meeting with Atletico Madrid at Anfield on Wednesday evening.
