Palace head to Anfield having secured Emirates FA Cup glory last weekend. Oliver Glasner's men overcame Manchester City 1-0 at Wembley to win the first major trophy in club history.
In the Premier League, meanwhile, they have won two and drawn three of their last five matches – including a 4-2 defeat of Wolverhampton Wanderers on Tuesday night.
Ahead of the final round of games, Palace sit 12th in the standings, having gathered 52 points from their 37 top-flight fixtures.
In the Premier League, Jean-Philippe Mateta has been the key man in front of goal for the Eagles with 14 goals to his name – alongside two assists.
Eberechi Eze has eight goals and eight assists this term, Ismaila Sarr has struck on seven occasions, with six assists, while Daniel Munoz has four and five respectively.
In the reverse fixture earlier this season, Liverpool overcame Palace 1-0 at Selhurst Park in the Premier League.
Diogo Jota netted in the October clash in just the ninth minute, which proved enough to earn the spoils for the visitors.
Palace will be without defender Marc Guehi (eye) and midfielder Adam Wharton (concussion) for the trip to Anfield.
Full-back duo Ben Chilwell and Nathaniel Clyne are both ill and therefore doubtful for the fixture.
Palace head coach Glasner
"Everybody has looked good in training. We were in a great mood again. Everybody's laughing, maybe we didn't have the highest intensity in training, but it's also a three-game week for us.
"It was the final, then we played Tuesday, and again [Sunday], so huge credit to the players, how they played. Of course, afterwards we get the stats – they showed we were running five kilometres more than Wolves. It just shows the attitude and the character of this group.
"So, really very pleased with the performance, with the result. Now we want to show it again, our standards, and at Anfield, so we are looking forward to this game.
"It's when the league winner meets the FA Cup winner – it's a great ending of the season. Also big congratulations to Liverpool and Arne Slot for an amazing season and a well-deserved title."
